TITLE:
The Prognostic Value of BMI, Serum Glucose, Endometrial Echo Pattern and Uterine Artery Doppler Velocimetry as a Predictor for Endometrial Pathology in Women with Postmenopausal Bleeding (Prospective Observational Study)
AUTHORS:
Yehia A. Wafa, Ahmed T. Abd Alfattah, Mohammed Sayed Korany
KEYWORDS:
BMI, Serum Glucose, Endometrial Echo Pattern, Uterine Artery Doppler Velocimetry, Endometrial Pathology, Postmenopausal Bleeding
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.10 No.1,
December
31,
2019
ABSTRACT: Background: Post-menopausal bleeding is a warning sign that accounts for about 5% of
all outpatient gynaecologic visits and is a common indication for referral to
rapid access clinics because of the fear of underlying malignancy. Endometrial
malignancies differ from other malignancies in that early symptomization is
common, allowing early cure. Patients and Methods: During the study
period, 100 women with post-menopausal bleeding having inclusion criteria were evaluated in Al-Hussein University Hospital. For
each patient full history, general, abdominal and pelvic examination was
performed. Routine pre-operative investigations were done. Patients were
divided into four groups: Group 1 included 29 patients with endometrial polyp.
Group 2 included 34 patients with endometrial hyperplasia. Group 3 included 21
patients with atrophic endometrium. Group 4 included 16 patients with
endometrial carcinoma. Results: As regards the
predictive value of BMI, in the study there was a high statistical significance
in comparison between the endometrial carcinoma group and all other benign
groups. When discussing the predictive value of blood glucose level, in the
study there was a high statistical significance in comparison between the
endometrial carcinoma group and all other benign groups. It is worth to mention that the predictive value of endometrial thickness, in
the study, was with high statistical significance in comparison between the
endometrial carcinoma group and all other benign groups providing the highest
specificity and sensitivity. At the last the predictive value of uterine artery
velocimetry, in the study, was with high statistical significance in comparison between the
endometrial carcinoma group and all other benign groups. Conclusion: BMI, blood glucose level, endometrial thickness and uterine artery velocimetry
indices, improve the prediction of endometrial carcinoma in women with
post-menopausal bleeding.