TITLE:
Müllerian Adenosarcoma of the Vaginal Stump: A Case Report and Literature Review
AUTHORS:
Juan Li, Zhenling Duan, Ma Jing, Xiaotao Jing, Li Bian
KEYWORDS:
Endometriosis, Vaginal Stump, Müllerian Adenosarcoma, Case Report
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.9 No.11,
November
26,
2018
ABSTRACT: Müllerian
adenosarcomas are rare mixed tumors with low malignant potential, and occur
mainly in the uterus. Primary adenosarcomas arising in vaginal endometriosis
are even more rarely reported. We report a very rare case with Müllerian
adenosarcoma arising from vaginal endometriosis. A 43-year-old nulliparous woman
has a history of endometriosis. Due to two parallel fistulas in cervix,
severe endometriosis and adenosarcoma, she has undergone radical and multiple
surgeries. After the surgery, persistent vaginal vault masses were noticed, and
eight resections of the polyps at vaginal stump were performed. For the first
six resections, all the pathological examinations showed endometriosis. And the
last two resections demonstrated vaginal adenosarcoma. Transition between Müllerian
adenosarcoma and endometriosis was gradual. Finally, adenosarcoma associated
with endometriosis was diagnosed from recurrent vaginal masses. To our
knowledge, this report is the sixth case that primary adenosarcomas arising in vaginal
endometriosis. But chemo-therapy and radiation therapy were not taken and the patient remained in a good condition throughout the
9-year follow-up period. In addition, we present a review of the literature.
The diagnosis and treatment of the tumor are also discussed.