TITLE:
Pattern Recognition Methods Combined with Raman Spectra Applied to Distinguish Serums from Lung Cancer Patients and Healthy People
AUTHORS:
Yankun Li, Mingjing Jia, Xiangchao Zeng, Kenan Huang, Zhichao Bai
KEYWORDS:
Raman Spectroscopy, Pattern Recognition, Lung Cancer Identification, Serum
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.5 No.9,
September
20,
2017
ABSTRACT: Raman spectroscopy was used to distinguish the serums from lung cancer patients and healthy people, through spectral pretreatment method combined with pattern recognition methods including principal component analysis (PCA), partial least squares-discriminant analysis (PLS-DA), un-correlated linear discriminant analysis (ULDA), etc. Through the comparisons of the results, it can be found that ULDA and LDA combined with multiple scatter correction (MSC) pretreatment method successfully distinguish the patients of lung cancer and healthy people. The method has academic significance and promising clinical application value.