TITLE:
Antibacterial Activity of Pterocarpus osun L. on Multi-Drug Resistant (MDR) Escherichia coli from Wound Infections in Abeokuta, South-West Nigeria
AUTHORS:
Bode Ireti Shobayo, David Ajiboye Ojo, David Adejare Agboola
KEYWORDS:
Pterocarpus osun L., Antibacterial Activity, Multi-Drug Resistance, Wound
JOURNAL NAME:
Open Access Library Journal,
Vol.2 No.8,
August
20,
2015
ABSTRACT:
Pterocarpus osun plant has been used overtime in the indigenous system of medicine. In this study, methanol, ethanol and aqueous extracts of leaves of P. osun were examined against five Escherichia coli strains obtained from wounds. Antibacterial effect of the plant leaves, in the concentration of 100 mg/ml, was determined using disc diffusion method. Phytochemical screening of extracts of the leaves revealed the presence of phenols, flavonoids, tannins, terpenoids alkaloids, and glycosides. Leaves extracts of P. osun showed different zones of inhibition to the Escherichia coli isolates in the different solvents used. Results from this study showed that extracts of P.osun had broad spectrum of activity on the tested bacteria.