TITLE:
UV Spectrophotometric Assay Method for the Determination of Fluconazole Capsules
AUTHORS:
Safila Naveed, Maheen Nafees
KEYWORDS:
Fluconazole, Spectrophotometer, Assay
JOURNAL NAME:
Open Access Library Journal,
Vol.2 No.4,
April
15,
2015
ABSTRACT:
A very simple, accurate, rapid and economical UV spectrophotometric method
was developed for the estimation of fluconazole. The UV method permits a simple,
rapid and economical quantitation of fluconazole in capsule dosage form only. The
maximum absorbance of fluconazole was found to be 210 nm. Fluconazole, which is
available in Karachi in different brands within the pharmacies, was collected and
used for this assay method. The results showed that the assay results of the two
brands were in range. This study would turn out to be very beneficial and with this
simple and accurate method, one can easily determine fluconazole.