TITLE:
The Epidemiology of Adenovirus Associated Lower Respiratory Tract Infection in Hospitalized Children in Hangzhou City, China
AUTHORS:
Qi Zheng, Meiping Lu, Wei Li
KEYWORDS:
Adenovirus, Respiratory Infection, Epidemiology
JOURNAL NAME:
Open Access Library Journal,
Vol.2 No.2,
February
11,
2015
ABSTRACT:
This study was
performed to investigate the epidemiology of adenovirus related acute lower respiratory
tract infection in children through a large sample collection. Totally 76,518
patients admitted to Children’s Hospital Affiliated to Zhejiang University School
of Medicine were investigated from July 2006 to June 2012. Nasopharyngeal
aspirates were collected and examined by immunofluorescence assay to confirm
viral etiology. There were 479 patients positive for adenovirus (6.3‰) and pneumonia accounted for most of these
patients. The median age of adenovirus infected was 16 months and peaked at the
second six-month of life. Winter, spring and summer had the similar positive
rate, while autumn had the lowest occurrence rate. The detection rates of adenovirus
on each spring from 2007 to 2012 were 18.01‰,
5.73‰,
11.85‰,
6.35‰,
11.77‰ and 2.66‰, respectively, which indicated a prevalence
appearing once every two years.