Noguchi, T., Shinohara, A., Nishizawa, A., Asayama, M., Nakano, T., Hasegawa, M., Harada, K.-I., Nishizawa, T. and Shirai, M. (2009) Genetic Analysis of the Microcystin Biosynthesis Gene Cluster in Microcystis Strains from Four Bodies of Eutrophic Water in Japan. Journal of General and Applied Microbiology, 55, 111-123.
http://dx.doi.org/10.2323/jgam.55.111

has been cited by the following article:

• TITLE: Phylogenetic Analysis of Frequent Recombinant Region in Micropeptin Biosynthetic Gene Cluster among the Genus Microcystis

  AUTHORS: Tomoyasu Nishizawa, Takamasa Miura, Ayana Futamura, Makoto Shirai

  KEYWORDS: Cyanobacteria, Microcystis, Micropeptin Biosynthetic Gene, Phylogenetic Analysis

  JOURNAL NAME: Advances in Microbiology, Vol.6 No.5, April 27, 2016

  ABSTRACT: The gene cluster for the biosynthetic of a nonribosomal peptide, cyanopeptolins and micropeptin (MCN), was identified in Microcystis strains and halogenated MCN-producing Microcystis were found to possess the halogenase gene, mcnD, between nonribosomal peptide synthetase genes, mcnC and mcnE. A comparative sequence analysis of the mcn gene cluster between halogenated and non-halogenated MCN-producing strains revealed mosaic sequence traces from mcnD in the non-coding region between mcnC and mcnE in the latter strains. A phylogenetic analysis based on a 170-bp non-coding region including the mcnD traces suggests that the recombination events occurred in a particular region of the Microcystis’ mcn gene. This study provides novel insight into the ecological patterning of widespread Microcystis species.