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http://dx.doi.org/10.1117/12.841316

has been cited by the following article:

• TITLE: Stability of M13 Phage in Organic Solvents

  AUTHORS: Pouya Moghimian, Vesna Srot, Benoit P. Pichon, Sandra J. Facey, Peter A. van Aken

  KEYWORDS: M13 Phage, Organic Solvent, Structural Integrity, Self-Assembly, Electron Microscopy

  JOURNAL NAME: Journal of Biomaterials and Nanobiotechnology, Vol.7 No.2, April 14, 2016

  ABSTRACT: The effect of different types of organic solvents on the structural integrity of M13 phages has been directly visualized by transmission and scanning electron microscopy. The exposure of M13 phages to apolar hexane had no effect on the structure of the phages for up to 8 h. In contrast, phages showed ~10-fold contraction into rod-like I-forms and to flattened spheroids with ~12 nm diameter upon exposure to polar organic solvents. We show that this finding can be beneficial for the macromolecular self-assembly and in broader aspects, to enhance the spatial arrangement of desired inorganic nanoparticles in the rapidly developing field of virotronics.