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has been cited by the following article:

• TITLE: The Prognostic Significance of the Preoperative Platelet-Lymphocyte Ratio in Japanese Patients with Localized Breast Cancer

  AUTHORS: Hideya Takeuchi, Seiichi Fukuyama, Nobuhide Kubo, Shoji Hiroshige, Hirofumi Kawanaka, Yasuji Yoshikawa, Tokujiro Yano

  KEYWORDS: Platelet-Lymphocyte Ratio, Breast Cancer, Inflammation

  JOURNAL NAME: Advances in Breast Cancer Research, Vol.5 No.2, April 8, 2016

  ABSTRACT: Inflammation has been shown to be a factor in tumorigenesis. The circulating platelet to lymphocyte ratio (PLR) is a representative index of systemic inflammation. In this study, we analyzed the association between preoperative PLR levels and clinicopathological variables in two hundred sixty-four Japanese patients with localized breast carcinoma. We also evaluated the prognostic significance of preoperative PLR levels using the Cox proportional hazard model. Seventy-five patients (28.4%) had elevated PLR values, whereas 189 (71.6%) had depressed PLR values. The PLR correlated significantly with venous invasion (P