Xu, H.Y., Liu, Y.-J., Xu, M.-Y., Zhang, Y.-H., Zhang, J.-X. and Wu, Y.-J. (2012) Inactivation of the Bed Nucleus of the Stria Terminalis Suppresses the Innate Fear Responses of Rats Induced by the Odor of Cat Urine. Neuroscience, 221, 21-27.
http://dx.doi.org/10.1016/j.neuroscience.2012.06.056

has been cited by the following article:

• TITLE: 2,5-Dihydro-2,4,5-Trimethylthiazoline (TMT)-Induced Neuronal Activation Pattern and Behavioral Fear Response in GAD67 Mice

  AUTHORS: Kathrin Janitzky, Olaf Prellwitz, Herbert Schwegler, Yuchio Yanagawa, Thomas Roskoden

  KEYWORDS: Predator Odor, 2, 5-Dihydro-2, 4, 5-Trimethylthiazoline, c-fos mRNA In-Situ-Hybridization, Innate Fear, Freezing, GAD67 Mice

  JOURNAL NAME: Journal of Behavioral and Brain Science, Vol.5 No.7, July 27, 2015

  ABSTRACT: The synthetic predator odor 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) was used to induce innate fear in male GAD67 mice and behavioral changes were correlated with c-fos mRNA levels as marker for neuronal activation to reveal underlying activated fear circuits. Results show the same amount of increased freezing and decreased rearing and grooming behavior of TMT-exposed GAD67 mice and wild type littermates, and therefore suggest that heterozygous knock-in of GFP in the GAD67 gene that is associated with a fifty percent decreased GAD67 protein level in the brain, has no impact on TMT-induced behavioral effects. Exposure to TMT significantly increased the number of c-fos mRNA positive cells in the main olfactory bulb (MOB), the lateral septum (LS), the bed nucleus of the stria terminalis (BNST), the central amygdala (CeA), the anterior-ventral (MeAav), the anterior-dorsal (MeAad) and the posterior-ventral (MeApv) part of the medial amygdala in GAD67 mice. Thus, to further investigate the role of GABAergic neurons in TMT-induced uncontrollable stress responses GAD67 mice that provide the advantage of prelabeled GABAergic neurons through the GABA neuron specific expression of GFP could be a suitable model organism.