Koennecke, H.C., Belz, W., Berfelde, D., Endres, M., Fitzek, S., Hamilton, F., Kreitsch, P., Mackbert, B.M., Nabavi, D.G., Nolte, C.H., Pohls, W., Schmehl, I., Schmitz, B., von Brevern, M., Walter, G., Heuschmann, P.U., and for the Berlin Stroke Register Investigators (2011) Factors Influencing In-Hospital Mortality and Morbidity Inpatients Treated on a Stroke Unit. Neurology, 77, 965-972.
http://dx.doi.org/10.1212/WNL.0b013e31822dc795

has been cited by the following article:

• TITLE: Impact of Admission Hyperglycemia on Stroke-Associated Pneumoniain Acute Cerebral Hemorrhage: A Retrospective Observational Study

  AUTHORS: Tian-Hua Ren, Biao Yuan, Tie-Cheng Yang, Jian-Guo Li, Niu Chi, Qian-Wei Ren, Hong-Mei Shi, Dong-Ming Yu, Kai Shan, Li-Xia Li, Xiao-Yan Dong

  KEYWORDS: Acute Intracerebral Hemorrhage (ICH), Stroke-Associated Pneumonia (SAP), Hyperglycemia, Hemoglobin (Hb)A1C

  JOURNAL NAME: Open Journal of Emergency Medicine, Vol.3 No.1, July 23, 2015

  ABSTRACT: Background: Hyperglycemia is always seen amongst acute intra-cerebral hemorrhage (ICH) and usually has been reported in literature and studied in relation to mortality and poor recovery. However, literature specific to stroke-associated pneumonia (SAP) on this topic is very small. Further, how to differentiate the predictive value of hyperglycemia with and without abnormal HbA1C in such patients is still a matter of debate and no universal consensus. We evaluated hyperglycemia as a marker for SAP in patients with ICH to assess its usefulness as a potential predictor. Materials and methods: Clinical characteristics for a sample of 551 patients with acute ICH were collected from the Beijing Tiantan Hospital of Capital Medical University, Beijing, China. Possible associated risk factors of SAP were reviewed. Hyperglycemia and HbA1C on admission were the main hypothetic predictor, SAP occurring within the first 7 days is the primary outcome. Results: The cohort study includes 551 hospitalized patients. The prevalence of hyperglycemia was 52.5% and SAP occurred in 147 (26.7%). The incidence of SAP was higher in the group with hyperglycemia than those without hyperglycemia (37.7% versus 14.5%, p 6.5) (OR, 1.57; 95%CI, 0.81 - 3.23) had not been shown to be associated with SAP. Conclusions: In this hospital-based cohort of patients presenting with acute intra-hemorrhage, hyperglycemia on admission was associated significantly with SAP. The association was stronger for hyperglycemia with normal HgbA1C than for hyperglycemia with high HgbA1C. Hyperglycemia with normal HgbA1C might be a more sensitive predictor of early acute complication, such as SAP.