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has been cited by the following article:

• TITLE: Enhancement of Sister Chromatid Exchanges (SCEs) in Peripheral Blood Lymphocytes of Women with Polycystic Ovary Syndrome (PCOS) in Vitro

  AUTHORS: Evagelia Dafa, Maria Kontou, Tzegiaver B. Mantratzi, Emmanouel N. Kontomanolis, Nikoletta G. Koutlaki, Vasilios A. Liberis, Theodore S. Lialiaris

  KEYWORDS: Polycystic Ovary Syndrome, Proliferative Rate Index, Mitotic Index, Genotoxicity, Cytostaticity

  JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.5 No.7, July 15, 2015

  ABSTRACT: The aim of the present study was to determine the level of underlying DNA damage in females with PCOS. Twenty-two women with PCOS and twenty-two healthy controls were included in this study. Patients were further categorized into three phenotypic subgroups: Subgroup A, oligo/anovulation (ANOV) and polycystic ovaries (PCO); Subgroup B, hyperandrogenism (HA) as a main characteristic (HA + ANOV or HA + PCO); Subgroup C, all three conditions present (HA + ANOV + PCO). The frequency of sister chromatid exchanges (SCEs) was used as an index of cytogenetic damage. Proliferation rate index (PRI), mitotic index (MI), average generation time (AGT) and population doubling time (PDT) were also evaluated. A significant (p