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has been cited by the following article:

• TITLE: Indoor Particulate Matter Associated with Systemic Inflammation in COPD

  AUTHORS: S. Bose, N. N. Hansel, E. S. Tonorezos, D. L. Williams, A. Bilderback, P. N. Breysse, G. B. Diette, Meredith C. McCormack

  KEYWORDS: Particulate Matter, Indoor Pollution, Chronic Obstructive Pulmonary Disease (COPD)

  JOURNAL NAME: Journal of Environmental Protection, Vol.6 No.5, May 28, 2015

  ABSTRACT: Chronic obstructive pulmonary disease (COPD) is a chronic disease characterized by progressive airflow obstruction, along with pulmonary and systemic inflammation. Outdoor PM has been associated with morbidity and mortality in COPD but less is known about effects of indoor air quality. In former smokers with COPD, we investigated in-home PM effects on pulmonary and systemic inflammation, symptoms, and lung function. Participants underwent in-home air monitoring for two weeks and simultaneous health assessments. Median (IQR) PM2.5 was 9 (7) μg/m3. Increased indoor PM2.5 was associated with increased white blood cells, predominantly neutrophils and lymphocytes, suggesting that even relatively low indoor PM2.5 may elicit a systemic inflammatory response in COPD.