TITLE:
Discrimination of Wild-Grown and Cultivated Ganoderma lucidum by Fourier Transform Infrared Spectroscopy and Chemometric Methods
AUTHORS:
Ying Zhu, Augustine Tuck Lee Tan
KEYWORDS:
Ganoderma lucidum, Traditional Chinese Medicine, Fourier Transform Infrared Spectroscopy, Chemometrics, Principal Component Discriminant Analysis, Partial Least Squares Discriminant Analysis
JOURNAL NAME:
American Journal of Analytical Chemistry,
Vol.6 No.5,
April
24,
2015
ABSTRACT: Wild-grown Ganoderma lucidum (G. lucidum), a traditional Chinese
herbal medicine, is highly cherished and expensive for its medicinal
efficiency. This study targets the development of an accurate and effective
analytical method to distinguish wild-grown G.
lucidum from cultivated ones, which are of essential importance for the
quality assurance and estimation of its medicinal value. Furthermore, different
parts of G. lucidum have been studied
to examine the differences between wild-grown and cultivated ones. Fourier
transform infrared (FTIR) diffuse reflectance spectroscopy combined with the
appropriate chemometric method has been proven to be a rapid and powerful tool
for discrimination of wild-grown and cultivated G. lucidum with classification accuracy of 98%. The informative
spectral absorption bands for discrimination emphasized by the linear
diagnostic rule have provided quantitative interpretations of the chemical
constituents of wild-grown G. lucidum regarding its anticancer effects.