M. Rosler, R. Anand, A. Cicin-Sain, S. Gauthier, Y. Agid, P. Dal-Bianco, H. B. St?helin, R. Hartman, M. Gharabawi, “Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomized controlled trial,” Br. Med. J. Vol. 318, 1999, 633-640.

has been cited by the following article:

• TITLE: A Simple and Highly Efficient Enantioselective Synthesis of (S)-Rivastigmine

  AUTHORS: Veera R. Arava, Laxminarasimhulu Gorentla, Pramod K. Dubey

  KEYWORDS: Cholinergic Agent, Enantioselective, Highly Efficient, (S)-(-)-2-Methyl-2-Propane Sulfina-mide, (S)-Rivastigmine

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.1 No.2, June 30, 2011

  ABSTRACT: A highly efficient and convenient procedure for the enantioselective synthesis of (S)-Rivastigmine, a cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parkinson’s disease, is accomplished by the treatment of versatile, readily accessible (S)-(-)-2-methyl-2-propanesulfinamide with 3-hydroxyacetophenone. This protocol provides high yield and excellent enantiomeric excess in short step synthesis.