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http://dx.doi.org/10.3390/12030634

has been cited by the following article:

• TITLE: The First Synthesis of Sessiline

  AUTHORS: Viktor Ilkei, Kornél Faragó, Zsuzsanna Sánta, Miklós Dékány, László Hazai, Csaba Szántay Jr., Csaba Szántay, György Kalaus

  KEYWORDS: Sessiline, Acylaminocarbinol, Iminium Ion, Alkaloid Synthesis

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.4 No.5, December 26, 2014

  ABSTRACT: Sessiline is an alkaloid which is recently isolated from the fruits of Acanthopanax sessiliflorus. The molecule contains two five-membered heterocyclic units joined together by an acylaminocarbinol-ether type bond. Here, we describe the first, simple synthesis of sessiline from 5-hydroxypyrrolidin-2-one and 5-hydroxymethylfurfural, which are prepared from succinimide and furfuryl alcohol, respectively. The coupling reaction takes place on moderate heating under neat conditions.