TITLE:
Infections Following Kidney Transplant in Children: A Single-Center Study
AUTHORS:
Alexandre Fernandes, Liliana Rocha, Teresa Costa, Paula Matos, Maria Sameiro Faria, Laura Marques, Conceição Mota, António Castro Henriques
KEYWORDS:
CMV Infection, Immunosuppression, Kidney Transplantation, Urinary Tract Infections
JOURNAL NAME:
Open Journal of Nephrology,
Vol.4 No.3,
September
25,
2014
ABSTRACT: Introduction: Infections are a major cause of morbidity and mortality in pediatric patients undergoing kidney transplantation (KT). Aim and Methods: To determine the patterns of infectious complications during the first 6 months post transplantation, we report our single center experience with data from pediatric kidney recipients transplanted between 2006 and 2011. Results: Thirty-two children (20 males) were submitted to KT. The most common cause of end-stage renal disease (ESRD) was congenital anomalies of the kidney and urinary tract (CAKUT) accounting for 62%. Over the first 6 months post-transplant period, twenty-eight (87.5%) children developed a total of 77 infections, mainly urinary tract infections (UTI) (64.9%). CAKUT etiology of ESRD and UTI before KT increased the risk to develop more than one episode of UTI [71.4% vs. 14.3% and 81.8% vs. 18.2%, respectively; p