TITLE:
Primary Malignant Peripheral Nerve Sheath Tumor of the Breast—A Case Report
AUTHORS:
Mushtaq Chalkoo, Shahnawaz Ahangar, Asim Rafiq Laharwal, Aasim Mushtaq Patloo, Abbass Mohd, Shabir Ahmed Dar
KEYWORDS:
Breast Lump; Malignant Peripheral Nerve Sheath Tumor
JOURNAL NAME:
Surgical Science,
Vol.2 No.3,
May
18,
2011
ABSTRACT: Malignant peripheral nerve sheath tumor is a rare soft tissue sarcoma. Breast is an extremely rare location of this lesion and presentation as a breast lump in the absence of pain or previous benign neural tumor is even rarer. We report such a lesion in a 60 year-old female who presented with hard and painless breast lump for 2 years. Histopathology revealed a malignant spindle cell tumor of low grade potential. It was subsequently confirmed to be malignant peripheral nerve sheath tumor (MPNST) on the basis of immunopositivity for vimentin, neurone specific enolase and S-100.