Ubbink, D.T., Westerbos, S.J., Nelson, E.A., et al. (2008) A Systematic Review of Topical Negative Pressure Therapy for Acute and Chronic Wounds. The British Journal of Surgery, 95, 685-692.
http://dx.doi.org/10.1002/bjs.6238

has been cited by the following article:

• TITLE: Tumor Recurrence after Negative Pressure Wound Therapy: An Alert Call

  AUTHORS: Patricio Andrades, Manuel Figueroa, Sergio Sepúlveda, Susana Benitez, Cristian Erazo, Stefan Danilla

  KEYWORDS: Negative Pressure Wound Therapy, Vacuum Assisted Closure, Cancer, Recurrence

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.3 No.6, June 11, 2014

  ABSTRACT: In this report, we present a 22-year-old patient with soft tissue sarcoma of the lower extremity that developed wound dehiscence after surgery. Biopsy demonstrated negative margins for cancer. He was treated with negative pressure wound therapy for 6 weeks and started to present increased wound exudates, local pain and proliferating tissue that was positive for tumor recurrence. Consequently he underwent lower extremity amputation with hip disarticulation by the orthopedic team. Although we cannot determine with certainty a full causative relationship, it seems prudent to advise cautious use of negative pressure wound therapy in oncologic related wound beds.