Article citationsMore>>
Zhu, C.Q., Popova, S.N., Brown, E.R., Barsyte-Lovejoy, D., Navab, R., Shih, W., Li, M., Lu, M., Jurisica, I., Penn, L.Z., Gullberg, D. and Tsao, M.S. (2007) Integrin α11 regulates IGF2 expression in fibroblasts to enhance tumo-rigenicity of human non-small-cell lung cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 104, 11754-11759.
http://dx.doi.org/10.1073/pnas.0703040104
has been cited by the following article:
-
TITLE:
Interaction of calcium- and integrin-binding protein 1 with integrin α11 and its possible involvement in pulmonary fibrosis
AUTHORS:
Koji Yoshida, Ah-Mee Park, Shingen Ozaki, Hiroshi Munakata
KEYWORDS:
Calcium- and Integrin-Binding Protein 1; Fibrosis; Integrin α11; Yeast Two-Hybrid
JOURNAL NAME:
Advances in Biological Chemistry,
Vol.4 No.1,
February
27,
2014
ABSTRACT:
Integrin α11
(ITGA11) is one of the collagen-binding integrin α chains; however, its biological significance remains unknown. To determine
the functions of ITGA11, we performed a yeast two-hybrid screen using the
cytoplasmic domain of ITGA11 as bait and transformed an EGY48 yeast strain with
the bait-containing plasmid using the plasmid from a human lung fibroblast
cDNA library. This screen identified calcium- and integrin-binding protein 1 (CIB1)
as prey. Recombinant ITGA11 and CIB1 were expressed in mammalian cells and
used in coimmunoprecipitation experiments, which showed that full-length
ITGA11 and CIB1 are also associated in
vivo. Over-expression of CIB1 in the human lung myofibroblast MRC-5 cells
decreased the expression of α-smooth
muscle actin and fibronectin. Using a mouse model of pulmonary fibrosis (bleomycin-treatment),
we detected elevated expression of CIB1 in lung tissues compared with
controls. These data suggest that CIB1 may regulate pulmonary fibrosis in
concert with IT-GA11.
Related Articles:
-
Dong-Ping Jiang, Jun Yang, Hui-Feng Yuan, Yu-Quan Wu, Pei-Yong Qiu, Guang-Zhou Lu, Qing-Yong Chen
-
Hongcheng Wang, Xiu Lan, Benyan Song, Caixia Xin, Chao Wang, Hong Dai
-
Alexander Emmert, Angelika Oellerich, Laszlo Füzesi, Regina Waldmann-Beushausen, Hanibal Bohnenberger, Friedrich A. Schöndube, Bernhard C. Danner
-
Gallelli Luca, Falcone Daniela, Perri Mariarita, Erika Cione, Pelaia Girolamo, Mesuraca Maria, Terracciano Rosa, Spaziano Giuseppe, D’Agostino Bruno, Navarra Michele, Savino Rocco
-
Masaki Tomita, Takanori Ayabe, Eiichi Chosa, Takashi Asada, Kazuyo Tsuchiya, Kunihide Nakamura