TITLE:
Preoperative serum vascular endothelial growth factor correlated to three dimensional power Doppler indices in ovarian masses
AUTHORS:
Maged R. AbouSeeda, Ghada M. Mansour, Sahar S. Ez-Elarab
KEYWORDS:
Ovarian Cancer; Ovarian Mass; Three Dimensional Power Doppler; VEGF; VI; FI; VFI
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.4 No.3,
February
21,
2014
ABSTRACT:
Objective: To assess the preoperative serum levels of
vascular endothelial growth factor (VEGF) in ovarian masses compared to normal controls
and to find a correlation between VEGF and Doppler indices in ovarian masses. Methods:
The study was conducted from December 2009 to September 2012 in the oncology and
ultrasound units in department of obstetrics and gynecology, Ain Shams University
on 150 patients with ovarian masses. During preoperative workup, serum Ca-125
levels and serum VEGF levels were obtained. Ultrasonographic
examination included two and three dimensional power Doppler ultrasound (3DPD).
Laparotomic approaches were undertaken to obtain the final pathologic results. VEGF
was measured in one hundred normal cases as controls. Results: Final ovarian pathology
revealed seventy three malignant ovarian masses and seventy seven were benign. Serum
Ca-125 levels in malignant cases were higher compared to those in benign cases (p