TITLE:
Solvent-Free Synthesis of 5-Alkenyl-2,2-butylidene-1, 3-dioxane-4,6-diones under Ultrasonic Irradiation with o-Phthalimide-N-Sulfonic Acid as Catalyst
AUTHORS:
Chunhua Lin, Zhaohui Xu, Weilin Liao
KEYWORDS:
o-Phthalimide-N-Sulfonicacid; 5-Alkenyl-2, 2-butylidene-1, 3-dioxane-4, 6-diones; Aromatic Aldehydes; Knoevenagel Condensation
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.3 No.4,
December
31,
2013
ABSTRACT:
5-Alkenyl-2,2-butylidene-1,3-dioxane-4,6-diones were synthesized by the Knoevenagel condensation reaction of aromatic aldehydes with 2,2-butylidene-1,3-dioxane-4,6-dione using o-phthalimide-N-sulfonic acid as catalyst, without solvent under ultrasonic irradiation. The present method has some notable advantages such as mild reaction conditions, short reaction times, less catalyst dosage and high yields with the green aspects by avoiding toxic catalysts and solvents. Further, the catalyst can be reused for five times without any noticeable decrease in the catalytic activity.