TITLE:
Biochemical and Neurobiological Study of Moroccan Autists
AUTHORS:
Hakim Harchaoui, Fatima-Zahra Azzaoui, Ahmed Ahami, Samira Boulbaroud, Mohamed El Hioui
KEYWORDS:
Autism; Neurobiology; Organic Acids; Toxic Metals; Essential Elements
JOURNAL NAME:
Neuroscience and Medicine,
Vol.4 No.4,
December
9,
2013
ABSTRACT:
Autism spectrum disorder (ASD) is a range of complex
neurodevelopment disorders, characterized by social impairments, communication difficulties, and restricted, repetitive, and
stereotyped patterns of behavior. Its diagnosis is very difficult and consists
of only clinical criteria. The aim of this study is to confirm autism
disorder, among three children (2 girls and 1 boy), recruited in a
social association of children in a precarious situation, located in Rabat,
Morocco, and to evaluate some biological and neurobiological parameters among
these children. The confirmation of autistic status is realized using
Questionnaire (E2) and the evaluation of biological parameters (organic acids,
urinary peptides, toxic metals and essential elements) is done in urine and
hair of these children. Obtained children’s scores of E2 Questionnaire, is found in the favor of autism. Moreover, abnormal levels of urinary
organic acids, urinary peptides, toxic and essential metals are observed.