TITLE:
Garlic Clove Catalyzed Biginelli Reaction in Water at Ambient Temperature
AUTHORS:
Hishame Abd-Elnabi, Afaf Mohamed Abdel Hameed, Ramadan Ahmed Mekheimer, Reham R. Awed, Kamal Usef Sadek
KEYWORDS:
Garlic Glove; Biocatalysis; Water; Biginelli Reaction
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.3 No.4,
November
22,
2013
ABSTRACT:
A simple, green and highly efficient procedure for the Biginelli condensation
reaction of aldehydes, β-ketoesters, urea or thiourea catalyzed by
crushed garlic clove at ambient temperature is reported.