TITLE:
The formulation for cancer prevention & therapy
AUTHORS:
Jerry T. Thornthwaite, Hare R. Shah, Pasupati Shah, William C. Peeples, Henry Respess
KEYWORDS:
Cancer Prevention; Formulation
JOURNAL NAME:
Advances in Biological Chemistry,
Vol.3 No.3,
June
25,
2013
ABSTRACT:
Our natural product research over nine years has been to
discover effective over-the-counter-supplements, designed to facilitate
classical treatments in fighting disease, specifically cancer. These supplements
are important in antiangiogenic, immune and antioxidant defense systems. The
components include Acetyl L-Carnitine (ALC), Alpha Lipoic Acid (ALA), Coenzyme
Q10 (CoQ10), Curcumin with Piperine, Genistein, Lentinan, N-Acetylcysteine (NAC),
Resveratrol, selenium, Vitamin B Complex, Vitamin C, Vitamin E and zinc.
These supplement components are supported for human cancer by over 15,000 references
in the scientific literature withover of these being published clinical trials,
not including zinc and the vitamins. These chemical defined components from
natural origins have demonstrated, either individually or collectively, to
have antioxidant, anti-angiogenesis, and immune stimulation properties. Furthermore,
the direct cancer cell cytotoxicity for Curcumin, Genistein and NAC have been
shown. Some of the antiangiogenesis components that affect the majority if
not all pathways of angiogenesis, such as Curcumin, Genistein and NAC, actually
stimulate the in vivo production of natural antiangiogenic compounds
that include Angiostatin, Endostatin and Thrombospotin 1. All of the components
play a role in serving as either water or lipid soluble (able to cross the
blood-brain barrier) antioxidants. Curcumin, Genistein, Resveratrol,
Lentinan, NAC, zinc, selenium and vitamins B and C all stimulate the immune
system. Except for ALC and CoQ10, the other components show anti-inflammatory
activity. ALC, Resveratrol along with the B and C vitamins are helpful in
treating fatigue. The components that help protect the brain and promote nerve
regeneration include ALA, CoQ10, Resveratrol, NAC, selenium, zinc and the B and
C vitamins. In conclusion, effective prevention and treatment for diseases
such as cancer, heart disease and immune deficiency will require multiple
compounds.