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http://dx.doi.org/10.1007/s10384-011-0004-8

has been cited by the following article:

• TITLE: IL-4, IL-6, IL-10, IL-17A and vascular endothelial growth factor in the vitreous of patients with proliferative diabetic retinopathy

  AUTHORS: Valery Chernykh, Evgeny Smirnov, Yegor Varvarinsky, Dmitry Chernykh, Olga Obukhovа, Aleksandr Trunov

  KEYWORDS: Diabetic Retinopathy; Cytokines; Vascular Endothelial Growth Factor

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.5 No.3, January 29, 2014

  ABSTRACT: In current article, results of the determination of the concentrations of vascular endothelial growth factor (VEGF), and some interleukins (IL-4, IL-6, IL-10, IL-17А) in the vitreous of patients with proliferative diabetic retinopathy are presented. We have found that in the mechanism of development of diabetic retinopathy, significant role plays an activation of local inflammation process and vascular proliferation. This is evidenced by a significant increase in the vitreous concentration of IL-4, IL-6, IL-10, IL-17A and vascular endothelial growth factor. Identified correlations between VEGF and IL-17A, between VEGF and IL-4, and between IL-17A and IL-4 show the relationship of inflammation and proliferation processes in the pathogenesis of diabetic retinopathy.