Conference on Environmental Pollution and Public Health (CEPPH 2010 E-BOOK)

Wuhan,China,China,9.10-9.12,2010

ISBN: 978-1-935068-16-7 Scientific Research Publishing, USA

E-Book 1502pp Pub. Date: October 2010

Category: Engineering

Price: $80

Title: Acute Toxicity and Influence on Micronucleus of Mice Bone Marrow of TDI
Source: Conference on Environmental Pollution and Public Health (CEPPH 2010 E-BOOK) (pp 249-250)
Author(s): Lei Yu, Center for Life Science and Environment Science, Harbin University of Commerce, Harbin, China, 150076/Workstation for Post-doctoral Scientific Research, Drug Research Center of Harbin University of Commerce, Harbin, China,150076/Natural Anti-tumor Drug Eng
Lin-jing Shen, Center for Life Science and Environment Science, Harbin University of Commerce, Harbin, China, 150076
Shi-yong Gao, Center for Life Science and Environment Science, Harbin University of Commerce, Harbin, China, 150076/Workstation for Post-doctoral Scientific Research, Drug Research Center of Harbin University of Commerce, Harbin, China,150076/Natural Anti-tumor Drug Eng
Chen-feng Ji, Center for Life Science and Environment Science, Harbin University of Commerce, Harbin, China, 150076/Workstation for Post-doctoral Scientific Research, Drug Research Center of Harbin University of Commerce, Harbin, China,150076/Natural Anti-tumor Drug Eng
Xiang Zou, Center for Life Science and Environment Science, Harbin University of Commerce, Harbin, China, 150076/Workstation for Post-doctoral Scientific Research, Drug Research Center of Harbin University of Commerce, Harbin, China,150076/Natural Anti-tumor Drug Eng
Miao Yu, Center for Life Science and Environment Science, Harbin University of Commerce, Harbin, China, 150076/Workstation for Post-doctoral Scientific Research, Drug Research Center of Harbin University of Commerce, Harbin, China,150076/Natural Anti-tumor Drug Eng
Yu-bin Ji, Center for Life Science and Environment Science, Harbin University of Commerce, Harbin, China, 150076/Workstation for Post-doctoral Scientific Research, Drug Research Center of Harbin University of Commerce, Harbin, China,150076/Natural Anti-tumor Drug Eng
Abstract: Oral acute toxicity of 2, 4-tolyene diisocyanate (TDI in short) on mice and its influence on micronucleus frequency of mice bone marrow were studied. And the results showed that the LD50 of TDI on mice orally was 1995mg/kg, and at the dosage of 1/2 LC50, 1/4 LC50, the difference was significant compared with the negative group.
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