Proceedings of the 7th National Conference on Functional Materials and Applications (FMA 2010 E-BOOK)

Changsha,China,10.16-10.18,2010

ISBN: 978-1-935068-41-9 Scientific Research Publishing, USA

E-Book 2313pp Pub. Date: October 2010

Category: Chemistry & Materials Science

Price: $360

Title: Chitosan-Grafted Multi-Walled Carbon Nanotubes for Sustained Releasing of Pazufloxacin Mesilate
Source: Proceedings of the 7th National Conference on Functional Materials and Applications (FMA 2010 E-BOOK) (pp 2233-2236)
Author(s): Jin-gang Yu, College of Chemistry and Chemical Engineering, Central South University, Changsha, China College of Science, Honghe University, Honghe, China
Ke-long Huang, College of Chemistry and Chemical Engineering, Central South University, Changsha, China College of Science, Honghe University, Honghe, China
Du-shu Huang, College of Chemistry and Chemical Engineering, Central South University, Changsha, China College of Science, Honghe University, Honghe, China
Jin-chun Tang, College of Chemistry and Chemical Engineering, Central South University, Changsha, China College of Science, Honghe University, Honghe, China
Abstract: Chitosan modified multiple-walled carbon nanotubes (MWCNT-CS) and chitosan (CS) semiinterpenetrating (semi-IPN) hydrogels were prepared according to different contents of MWCNT-CS in MWCNT-CS/CS. The so prepared semi-IPN hydrogels were used as drug carriers. Pazufloxacin mesilate (PZFX) was loaded to the semi-IPN hydrogels, and the effects of the contents of MWCNT-CS in MWCNTCS/ CS and the pH values of the buffers to the loading and releasing ability of semi-IPN hydrogels were further studied. The mechanism of PZFX releasing from the hydrogels was also discussed.
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