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Author(s): |
Lei Chen, Zhuzhou Times New Material Technology Co., Ltd., Zhuzhou 412007, China
Qiang-jun Li, Zhuzhou Times New Material Technology Co., Ltd., Zhuzhou 412007, China
Qi-bin Jiang, Zhuzhou Times New Material Technology Co., Ltd., Zhuzhou 412007, China
Xue-si Chen, Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry,Chinese Academy of Sciences, Changchun 130022, China |
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Abstract: |
This electronic Magnetic nanopaticles (MNP) were prepared via a co-precipitation process, and its surface was functionalized by silanization reaction with (3-aminopropyl) triethoxysilane (APTES). Then, the magnetic nanopaticles grafting hydrophobic poly(amino acids) (MNP-PBLG) were synthesized by surface- initiated ring-opening polymerization of N-carboxyanhydride of γ-benzyl-L-glutamate (BLG-NCA) in DMF. The morphology and structure information were characterized by the measure of FT-IR, TGA, SEM, etc. Prepared novel magnetic core-shell nanoparticles have a good potential as intelligent carriers in drug delivery.
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