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Author(s): |
Zu-de Feng, College of Materials, Xiamen University , Xiamen, China
Xiao-juan Chi, College of Materials, Xiamen University , Xiamen, China
Jing-jing Sun, College of Materials, Xiamen University , Xiamen, China
Yu-xing Song, College of Materials, Xiamen University , Xiamen, China
Ying Ma, College of Materials, Xiamen University , Xiamen, China |
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Abstract: |
Preservable root canal sealer had received extensive attention because of its well application in the therapy of pulpitis and periapical periodontitis. The objective of this study was to develop a new kind of preservable root canal sealer based on calcium phosphate cement (CPC). Metronidazole-loaded mesoporous calcium- stabilized zirconia, as a developer, was added to increase the sterilizing effect and exhibited good radiopacity and sealing ability. The physicochemical properties of sealer had no obvious change during two months when premixed and stored at 4℃, 50% relative humidity (RH). With the addition of moist agent and gelling agent, the workability and the microstructure of sealer hardly changed in two months after being stored at 4℃, 50% RH and the metronidazole could be released slowly so as to inhibit the growth of bacteria.
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