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Proceedings of the 7th National Conference on Functional Materials and Applications (FMA 2010 E-BOOK)

Changsha,China,10.16-10.18,2010

ISBN: 978-1-935068-41-9 Scientific Research Publishing, USA

E-Book 2313pp Pub. Date: October 2010

Category: Chemistry & Materials Science

Price: $360

Title: Antibacterial and Antioxidant Properties of N-Carboxyethyl Chitosan
Source: Proceedings of the 7th National Conference on Functional Materials and Applications (FMA 2010 E-BOOK) (pp 1343-1346)
Author(s): Chang-jiang Yu, Ministry of Education Key Laboratory of Application Technology of Hainan Superior Resources Chemical Materials, Hainan university,
Qiang Lin, Ministry of Education Key Laboratory of Application Technology of Hainan Superior Resources Chemical Materials, Hainan university,
Wen Yuan, Ministry of Education Key Laboratory of Application Technology of Hainan Superior Resources Chemical Materials, Hainan university,
Fang Liu, Ministry of Education Key Laboratory of Application Technology of Hainan Superior Resources Chemical Materials, Hainan university,
Abstract: chitosan is the only alkaline natural polysaccharide, which expresses good bioactivities. In this paper, chitosan was modified with pyruvic acid to get N-carboxyethyl chitosan (N-CE-CTS) which was supposed to have better solubility and bioactivities than chitosan. N-CE-CTS with DS 40.1% dissolves in water. Antioxidant activity was measured with electron spinning resonance (ESR). The results show that N-CE-CTS has better antioxidant activity than chitosan. The antioxidant activity of 2 mg/mL N-CE-CTS and chitosan is 35.0% and 30.1%, respectively. N-CE-CTS has good antibacterial activity against Staphylococcus aureus and Escherichia coli. However antibacterial activity of N-CE-CTS is a little lower than that of chitosan. Antioxidant and antibacterial activity of N-CE-CTS and chitosan increase with the increase of concentration of N-CE-CTS and chitosan.
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