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Proceedings of the 7th National Conference on Functional Materials and Applications (FMA 2010 E-BOOK)

Changsha,China,10.16-10.18,2010

ISBN: 978-1-935068-41-9 Scientific Research Publishing, USA

E-Book 2313pp Pub. Date: October 2010

Category: Chemistry & Materials Science

Price: $360

Title: Fabrication and Characterization of Silk Fibroin/CaSiO3 Composite Scaffolds
Source: Proceedings of the 7th National Conference on Functional Materials and Applications (FMA 2010 E-BOOK) (pp 334-337)
Author(s): Hai-lin Zhu, The Key Laboratory of Advanced Textile Materials and Manufacturing Technology, College of Materials and Textiles; Zhejiang Sci-Tech University, Hangzhou 310018
Bin-wei Wu, The Key Laboratory of Advanced Textile Materials and Manufacturing Technology, College of Materials and Textiles; Zhejiang Sci-Tech University, Hangzhou 310018
Xin-xing Feng, The Key Laboratory of Advanced Textile Materials and Manufacturing Technology, College of Materials and Textiles; Zhejiang Sci-Tech University, Hangzhou 310018
Jian-yong Chen, The Key Laboratory of Advanced Textile Materials and Manufacturing Technology, College of Materials and Textiles; Zhejiang Sci-Tech University, Hangzhou 310018
Abstract: Silk fibroin/CaSiO3 composite scaffolds were prepared by solvent casting-particulate leaching method. The as-prepared composite scaffolds showed high porosity and interconnected pores of about 150-300 μm in diameter. XRD analysis suggested that the SF was in Silk II structure. The compressive modulus and compressive strength of composite scaffolds decreased along with the increase of the content of porogen, but the porosity showed opposite trend. XRD, field emission scanning electron microscopy (FESEM) and energy-dispersive spectrometer (EDS) analysis showed that the composite scaffold was completely covered by hydroxycarbonate apatite layers after soaking in SBF for 7 days. All these results indicated that the silk fibroin/CaSiO3 composite scaffold may be potential candidates as bioactive scaffold for tissue repair and tissue engineering application.
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