Interaction between Primary Care Physicians and Specialists for Diagnosis and Management of Hypersensitivity Pneumonitis

Abstract

Objective: Hypersensitivity pneumonitis (HP) may be a complex syndrome rather than a single, uniform disease entity. The problems associated with HP treatment include a lack of awareness of primary care procedures and scarcity of recent information regarding HP. The main objective of this study was to investigate the problems in the interaction between primary care physicians and chest specialists. Data source: All available clinical records of cases at the Fukujuji Chest Hospital, Tokyo, between 1994 and 2005, supervised by specialists of a university hospital. Study selection: All cases suspected of HP during the period. Results: Nine cases were excluded because of insufficient records or because they did not satisfy the clinical criteria. Twenty-eight enrolled patients (14 men and 14 women; mean age, 53.0 years) were initially treated for respiratory infections by primary care physicians. The final HP types were summer-type (n = 18), bird fancier’s lung (n = 2), ventilation-related (n = 3), or undetectable antigen (n = 5). On the basis of the interval between the onset of initial symptoms and the time of referral to our hospital, the cases can be categorized into 3 groups, which may represent acute, subacute, and chronic HP. Conclusion: All patients initially received treatment on the basis of a different diagnosis at primary evaluation. We concluded that interaction between primary care physicians and chest specialists is essential for solving problems associated with the early diagnosis and adequate treatment of HP.

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K. Morii, K. Yoshimori, M. Sudo, H. Ogata, M. Okumura, A. Gemma, S. Kudoh and K. Kida, "Interaction between Primary Care Physicians and Specialists for Diagnosis and Management of Hypersensitivity Pneumonitis," International Journal of Clinical Medicine, Vol. 2 No. 4, 2011, pp. 444-451. doi: 10.4236/ijcm.2011.24074.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Y. Cormier and Y. Lacasse, “Keys to the Diagnosis of Hypersensitivity Pneumonitis: The Role of Serum Precipitins, Lung Biopsy, and High-Resolution Computed Tomography,” Clinical Pulmonary Medicine, Vol. 3, No. 2, 1996, pp. 72-77.
[2] C. Rose and T. E. King Jr., “Controversies in Hypersensitivity Pneumonitis,” The American Review of Respiratory Disease, Vol. 145, No. 1, 1992, pp. 1-2.
[3] M. Selman, “Hypersensitivity Pneumonitis,” In: T. E. King Jr. and M. I. Schwarz, Eds., Interstitial Lung Disease, 4th Editoin, BC Decker, Hamilton, 2003, p. 452.
[4] M. Ando, K. Arima, R. Yoneda and M. Tamura, “Japanese Summer-Type Hypersensitivity Pneumonitis. Geographic Distribution, Home Environment, and Clinical Characteristics of 621 Cases,” The American Review of Respiratory Disease, Vol. 144, No. 4, 1991, pp. 765-769.
[5] M. Ando, K. Konishi, R. Yoneda and M. Tamura, “Difference in the Phenotypes of Bronchoalveolar Lavage Lymphocytes in Patients with Summer-Type Hypersensitivity Pneumonitis, Farmer’s Lung, Ventilation Pneumonitis, and Bird Fancier’s Lung: Report of a Nationwide Epidemiologic Study in Japan,” Journal of Allergy and Clinical Immunology, Vol. 87, No. 5, 1991, pp. 1002- 1009.
[6] K. Yoshida, M. Suga, Y. Nishiura, K. Arima, R. Yoneda, M. Tamura and M. Ando, “Occupational Hypersensitivity Pneumonitis in Japan: Data on a Nationwide Epidemiological Study,” Occupational and Environmental Medicine, Vol. 52, No. 9, 1995, pp. 570-574.
[7] H. B. Richerson, I. L. Bernstein, J. N. Fink, G. W. Hunninghake, H. S. Novey, C. E. Reed, J. E. Salvaggio, M. R. Schuyler, H. J. Schwartz and D. J. Stechschulte, “Guidelines for the Clinical Evaluation of Hypersensitivity Pneumonitis. Report of the Subcommittee on Hypersensitivity Pneumonitis,” Journal of Allergy and Clinical Immunology, Vol. 84, No. 5, 1989, pp. 839-844.
[8] L. C. Mohr, “Hypersensitivity Pneumonitis,” Current Opinion in Pulmonary Medicine, Vol. 10, No. 5, 2004, pp. 401-411.
[9] Y. Yoshizawa, Y. Ohtani, H. Hayakawa, A. Sato, M. Suga and M. Ando, “Chronic Hypersensitivity Pneumonitis in Japan: A Nationwide Epidemiologic Survey,” Journal of Allergy and Clinical Immunology, Vol. 103, No. 2, 1999, pp. 315-320.
[10] N. Kohno, “Serum Marker KL-6/MUC1 for the Diagnosis and Management of Interstitial Pneumonitis,” Journal of Investigative Medicine, Vol. 46, No. 3-4, 1999, pp. 151- 158.
[11] L. S. Newman, K. Kreiss, T. E. King Jr., S. Seay and P. A. Campbell, “Pathologic and Immunologic Alterations in Early Stages of Beryllium Disease: Reexamination of Disease Definition and Natural History,” American Review of Respiratory Disease, Vol. 139, No. 6, 1989, pp. 1479-1486.
[12] M. L. Muilenberg, “Aeroallergen Assessment by Microscopy and Culture,” Immunology and Allergy Clinics of North America, Vol. 9, No. 2, 1989, pp. 245-268.
[13] Y. Lacasse, M. Selman, U. Costabel, J. C. Dalphin, M. Ando, F. Morell, R. Erkinjuntti-Pekkanen, N. Muller, T. V. Colby, M. Schuyler, Y. Cormier and HP Study Group, “Clinical Diagnosis of Hypersensitivity Pneumonitis,” American Journal of Respiratory and Critical Care Medicine, Vol. 168, No. 8, 2003, pp. 952- 958.
[14] C. S. Glazer, C. S. Rose and D. A. Lynch, “Clinical and Radiologic Manifestations of Hypersensitivity Pneumonitis,” Journal of Thoracic Imaging, Vol. 17, No. 4, 2002, pp. 261-272.
[15] K. M. Bang, D. N. Weissman, G. A. Pinheiro, V. C. Antao, J. M. Wood and G. Syamlal, “Twenty-Three Years of Hypersensitivity Pneumonitis Mortality Surveillance in the United States,” American Journal of Industrial Medicine, Vol. 49, No. 12, 2006, pp. 997-1004.
[16] K. H. Dangman, S. R. Cole, M. J. Hodgson, C. Kuhn, M. L. Metersky, P. Schenck and E. Storey, “The Hypersensitivity Pneumonitis Diagnostic Index: Use of Non-invasive Testing to Diagnose Hypersensitivity Pneumonitis in Metalworkers,” American Journal of Industrial Medicine, Vol. 42, No. 2, 2002, pp. 150-162.
[17] M. J. Hodgson, D. K. Parkinson and M. Karpf, “Chest X-Rays in Hypersensitivity Pneumonitis: A Metaanalysis of Secular Trend,” American Journal of Industrial Medicine, Vol. 16, No. 1, 1989, pp. 45-53.
[18] E. Pozzi, “Extrinsic Allergic Alveolitis (Hypersensitivity pneumonitis),” In: C. Grassi, C. Brambella, U. Costabel, R. A. Stockley, R. Naeije and R. Rodriguez-Roisin, Eds., Pulmonary Diseases, McGraw-Hill International (UK) Ltd, London, 1999, pp. 289-294.
[19] Y. Ohtani, J. Ochi, K. Mitaka, T. Takemura, T. Jinta, J. Kuramochi, Y. Miyazaki, N. Inase and Y. Yoshizawa, “Chronic Summer-Type Hypersensitivity Pneumonitis Initially Misdiagnosed as Idiopathic Interstitial Pneu- monia,” Internal Medicine, Vol. 47, No. 8, 2008, pp. 857- 862.
[20] Y. Ohtani, S. Saiki, Y. Sumi, N. Inase, S. Miyake, U. Costabel and Y. Yoshizawa, “Clinical Features of Re- current and Insidious Chronic Bird Fancier’S Lung,” Annals of Allergy, Asthma & Immunology, Vol. 90, No. 6, 2003, pp. 604-610.
[21] Y. Ohtani, S. Saiki, M. Kitaichi, Y. Usui, N. Inase, U. Costabel and Y. Yoshizawa, “Chronic Bird Fancier’S Lung: Histopathological and Clinical Correlation. An Application of the 2002 ATS/ERS Consensus Classification of the Idiopathic Interstitial Pneumonias,” Thorax, Vol. 60, No. 8, 2005, pp. 665-671.
[22] N. Inase, Y. Ohtani, Y. Usui, Y. Miyazaki, T. Takemura and Y. Yoshikawa, “Chronic Summer-Type Hypersensitivity Pneumonitis: Clinical Similarities to Idiopathic Pulmonary Fibrosis,” Sarcoidosis Vasculitis Diffuse Lung Diseases, Vol. 24, No. 2, 2007, pp. 141-147.
[23] K. Arima, M. Ando, K. Ito, T. Sakata, T. Yamaguchi, S. Araki, M. Futatsuka, “Effect of cigarette smoking on prevalence of summer-type hypersensitivity pneumonitis caused by Trichosporon cutaneum,” Archives of Occupational and Environmental Health, Vol. 47, No. 4, 1992, pp. 274-278.
[24] B. van den Blink, M. S. Wijsenbeek and H. C. Hoogsteden, “Serum Biomarkers in Idiopathic Pulmonary Fibrosis,” Pulmonary Pharmacology and Therapeutics, Vol. 23, No. 6, 2010, pp. 515-520.
[25] A. Ramírez-Venegas, R. H. Sansores, R. Pérez-Padilla, G. Carrillo and M. Selman, “Utility of a Provocation Test for Diagnosis of Chronic Pigeon Breeder’s Disease,” American Journal of Respiratory and Critical Care Medicine, Vol. 158, No. 3, 1998, pp. 862-869.
[26] Y. Ohtani, K. Kojima, Y. Sumi, M. Sawada, N. Inase, S. Miyake and Y. Yoshizawa, “Inhalation Provocation Tests in Chronic Bird Fancier’S Lung,” Chest, Vol. 118, No. 5, 2000, pp. 1382-1389.

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