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Green and High Efficient Synthesis of 2-Aryl Benzimidazoles: Reaction of Arylidene Malononitrile and 1,2-Phenylenediamine Derivatives in Water or Solvent-Free Conditions

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DOI: 10.4236/ijoc.2015.54025    4,085 Downloads   5,283 Views  

ABSTRACT

A fast, high efficiency and environmentally friendly procedure for the synthesis of 2-aryl benzim-idazole derivatives has been reported. Reaction between 1,2-phenylenediamine derivatives and arylidene malononitrile under aqueous media and also solvent-free conditions generates 2-aryl benzimidazole derivatives with a high yield.

Conflicts of Interest

The authors declare no conflicts of interest.

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Habibi, A. , Valizadeh, Y. , Mollazadeh, M. and Alizadeh, A. (2015) Green and High Efficient Synthesis of 2-Aryl Benzimidazoles: Reaction of Arylidene Malononitrile and 1,2-Phenylenediamine Derivatives in Water or Solvent-Free Conditions. International Journal of Organic Chemistry, 5, 256-263. doi: 10.4236/ijoc.2015.54025.

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