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Metachronous double malignancy involving the kidney and the breast: A case report

DOI: 10.4236/crcm.2014.32016    3,836 Downloads   5,013 Views  

ABSTRACT

The occurrence of multiple primary cancers is rare; it can be missed as a disease progression. The etiology remains controversial. We report a case of a 55-year-old female with metastatic renal cell carcinoma treated with sutent followed by left sided nephrectomy. Follow-up CT showed increase in the size of the right axillary lymph nodes which was proven after biopsy to be metastatic adenocarcinoma of the breast. Any suspicious disease progression in a single site not compatible with disease history should be biopsied for confirmation. The relationship between renal cell carcinoma and breast cancer is still unclear, and more case reports are required to determine this relationship.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Ahmed, O. and Abbas, T. (2014) Metachronous double malignancy involving the kidney and the breast: A case report. Case Reports in Clinical Medicine, 3, 67-69. doi: 10.4236/crcm.2014.32016.

References

[1] Dalal, S., et al. (2008) Synchronous double malignancy: Adeno-carcinoma of caecum and renal cell carcinoma. The Internet Journal of Gastroenterology, 6, 4.
[2] Mesmoudi, M., et al. (2011) Triple malignancy in a single patient including a cervical carcinoma, a basal cell carcinoma of the skin and a neuroendocrine carcinoma from an unknown primary site: A case report and review of the literature. Journal of Medical Case Reports, 5, 462.
http://dx.doi.org/10.1186/1752-1947-5-462
[3] Cheng, J.H., et al. (2008) Double primary bronchogenic carcinoma of the lung and papillary thyroid carcinoma: A case report. Journal of Medical Case Reports, 2, 309.
http://dx.doi.org/10.1186/1752-1947-2-309
[4] Raissouni, S., et al. (2012) Radiation induced esophageal adenocarcinoma in a woman previously treated for breast cancer and renal cell carcinoma. BMC Research Notes, 5, 426. http://dx.doi.org/10.1186/1756-0500-5-426
[5] Fletcher, H., et al. (2007) Multiple metachronous malignancies, one patient with three primary malignancies: A case report. Journal of Medical Case Reports, 1, 15.
http://dx.doi.org/10.1186/1752-1947-1-15
[6] Albiges, L. and Escudier, B. (2011) Vascular endothelial growth factor-targeted therapy for the treatment of renal cell carcinoma. Drugs, 71, 1179.
http://dx.doi.org/10.2165/11591410-000000000-00000
[7] Aapro, M. (2009) Sunitinib and metastatic breast cancer. Advances in Oncology, 4, 18.
[8] Conley, S.J., et al. (2012) Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia. Proceedings of the National Academy of Sciences of USA, 109, 2784-2789.

  
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