Trace Elemental Analysis in Epileptic Children

Abstract

We have measured trace elements in epileptic patients. Levels of trace elements are very fluctuating in comparison to the healthy controls. The levels of Zn, Fe and Cu are higher in comparison to healthy normal children about 64%, 55% and 33% respectively. The levels of Cu are just fifty percent to levels of Zn. The levels of Ca, K and Mg are higher about 10%, 9.027% and 4.2% in comparison to normal children. Sodium levels were very low in comparison to all the trace elements and are higher about 3.2% than controls. The multiple correlation coefficients between Na, K and Ca, i.e. (RNa.KCa) has a value 0.4993 in comparison to healthy children. Multiple correlation coefficients between Fe, Cu and Zn, i.e. (RFe.CuZn) has a value 0.4366. The multiple correlation coefficients RNa.Kca and RFe.CuZn are found lower. These elements were strongly correlated with other. The multiple correlation coefficients such as RK.NaCa, RCa.K.Na, RMg.NaK, RNa.MgK, RK.MgNa, RCu.FeZn and RZn.FeCu were also evaluated and found on higher side from normal range. Trace elements may act as a catalytic agent for enzyme system of the cells. The minimum requirements of living objects for essential trace elements may be expressed in proportions or concentrations of the total dry food taken everyday. A tolerance of the human system may be fluctuated according to intake of these elements.

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S. Kumar, V. Kumar, R. Mittal and D. Jain, "Trace Elemental Analysis in Epileptic Children," Open Journal of Applied Sciences, Vol. 3 No. 8, 2013, pp. 449-476. doi: 10.4236/ojapps.2013.38056.

Conflicts of Interest

The authors declare no conflicts of interest.

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