Mechanism of Cuff-Less Blood Pressure Measurement Using MMSB

Yibin Li, Yangyu Gao, Ning Deng

Institute of Microelectronics, Tsinghua University, Beijing, 100084, China.

DOI: 10.4236/eng.2013.510B025                

Abstract

Continuous measurement of blood pressure based on pulse transit time (PTT) using GMR sensors is the state-of-art non-invasive cuffless method in which modulated magnetic signature of blood (MMSB) is used. In this paper, the mechanism of MMSB is investigated. According to the experimental results, it is found that both blood pulse flowing through the applied magnetic field and the displacement of the GMR sensor caused by blood pulse contribute to the disturbance of magnetic field detected by GMR sensors. The feasibility of MMSB method is discussed as well.

Keywords

Blood Pressure; Magnetic Sensor; Pulse Transit Time

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	C. T. Phua and G. Lissorgues, “Measurement of Blood Pressure Using Magnetic Method of Blood Pulse Acquisition,” Proceedings of the 2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, October 2009, Taiwan, pp. 112-115.
[2]	C. T. Phua, G. Lissorgues and B.Mercier, “Non-Invasive Acquisition of Blood Pulse using Magnetic Disturbance Technique,” Proceedings 23rd International Conference of Biomedical Engineering (ICBME), 2008, pp. 786-789.
[3]	J. Joseph, J. Venkataraman, V. Jagadeesh Kumar and S. Suresh, “Non-Invasive Estimation of Arterial Compliance,” IEEE International Instrumentation & Measurement Technology Conference (I2MTC), 2011, pp. 480- 484.
[4]	J. Joseph and V. Jayashankar, “Magnetic Sensor for Non-Invasive Detection of Blood Pulse and Estimation of Arterial Compliance,” 2010 IEEE EMBS Conference on Biomedical Engineering & Sciences (IECBES 2010), 30 November-2 December 2010, Kuala Lumpur, Malaysia, pp. 170-175.
[5]	F. L. Sinatra, “Understanding the Interaction between Blood Flow and an Applied Magnetic Field,” University of South Florida, 2010.
[6]	J. Joseph, V. Jayashankar and K. V. Jagadeesh, “A PC Based System for Non-Invasive Measurement of Carotid Artery Compliance,” 2009 IEEE Instrumentation & Measurement Technology Conference, Singapore, May 2009, pp. 656-661.
[7]	C. T. Phua and G. Lissorgues, “Modeling of Pulsatile Blood Flow in a Weak Magnetic Field,” Engineering and Technology, World Academy of Science, Vol. 54, 2009 pp. 73-76.
[8]	P. C. Teck, Lissorgues, “Non-Invasive Measurement of Blood Flow Using Magnetic Disturbance Method”, Gaelle 2009 International Conference on Biamedical and Pharmaceutical Engineering, pp. 80-83.
[9]	J. Labadin and A. Ahmadi, “Mathematical Modeling of the Arterial Blood Flow,” Proceedings of the 2nd IMT- GT Regional Conference on Mathematics, Statistics and Applications, University Sains Malaysia, Penang, June 2006, pp. 222-226.
[10]	H. Gesche, D. Grosskurth, G. Kuechler and A. Patzak, “Continuous Blood Pressure Measurement by Using the Pulse Transit Time: Comparison to a Cuff-Based Method,” European Journal of Applied Physiology, Vol. 112, No. 1, 2012, pp. 309-315. http://dx.doi.org/10.1007/s00421-011-1983-3
[11]	W. Chen, T. Kobayashi, S. Lchikawa, Y. Takeuchi and T. Togawa, “Continuous Estimation of Systolic Blood Pressure Using the Pulse Arrival Time and Intermittent Calibration,” Medical & Biological Engineering & Computing, Vol. 38, 2000, pp. 569-574. http://dx.doi.org/10.1007/BF02345755
[12]	L. A. Geddes, M. H. Voelz, C. E. Babbs and W. A. Tacker, “Pulse Transit Time as an Indicator of Arterial Blood Pressure,” Psychophysiology, Vol. 18, 1981, pp. 71-74. http://dx.doi.org/10.1111/j.1469-8986.1981.tb01545.x
[13]	J. S. Kim, Y. J. Chee, J. W. Park, J. W. Choi and K. Suk Park, “A New Approach for Non-Invasive Monitoring or Blood Pressure on a Toilet Seat,” Physiol.Means, Vol. 27, 2006, pp. 211-230.
[14]	Y. Yoon, J. H. Cho and G. Yoon, “Non-Constrained Blood Pressure Monitoring Using ECG and PPG for Personal Healthcare,” Journal of Medicine System, Vol. 33, 2009, pp. 261-266. http://dx.doi.org/10.1007/s10916-008-9186-0