Impact of urinary tract and pulmonary infection on mortality after intracerebral hemorrhage in Brazzaville

P. M. Ossou-Nguiet, B. F. Ellenga-Mbolla, A. S. W. Odzebe, G. F. Otiobanda, T. N. Gankama, K. Obondzo-Aloba, T. R. Gombet

Department of Cardiology, University Hospital of Brazzaville, Brazzaville, Congo.
Department of Medicine, Health Sciences Faculty of Brazzaville, Brazzaville, Congo.
Department of Medicine, Health Sciences Faculty of Brazzaville, Brazzaville, Congo&Department of Cardiology, University Hospital of Brazzaville, Brazzaville, Congo.
Department of Neurology, University Hospital of Brazzaville, Brazzaville, Congo.
Department of Neurology, University Hospital of Brazzaville, Brazzaville, Congo&Department of Medicine, Health Sciences Faculty of Brazzaville, Brazzaville, Congo.
Department of Surgery and Maternity, Faculty of Health Sciences of Brazzaville, Brazzaville, Congo.

DOI: 10.4236/wjns.2013.34033                

Abstract

Objective: To evaluate the impact of urinary tract and pulmonary infection on mortality after cerebral hemorrhage. Method: We conducted at the University Hospital of Brazzaville, a cross-sectional study from January to August2012 inthe emergency department, neurology and intensive care unit. It included patients admitted for cerebral hemorrhage confirmed by CT-scan. A statistical analysis by logistic regression was carried out to evaluate the correlation between infection and death. Result: Among total of 261 patients for stroke, 82 admitted for cerebral hemorrhage (31.4%). The mean age was 55 ± 11 years (range 26 to 83 years). The sex ratio men/women was 1.7. Hypertension was the most important risk factor to 80.5%. The average intake in neurology time was 28 ± 13 hours. The average time for completion of the CT-scan was 2.4 ± 2 days. Thirty-eight (46.3%) patients had a fever linked to an infectious cause from the third day of hospitalization. The most frequent infectious complications were sepsis (n = 16%; 42%), pulmonary infection (n = 14%; 37%) and urinary tract infection (n = 8%; 21%). Specific mortality of infection was 31.7% (n = 26). The multivariate analysis showed a positive correlation between the occurrence of infection and mortality (p = 0.002), specifically between sepsis and mortality (p = 0.0004), and an association between the time of admission late in neurology and the occurrence of infectious complications (p = 0.0001). Conclusion: Infection is one of the dreaded complications of cerebral hemorrhage. It is often associated with delayed care in specialized areas, and is thereby a preventable cause of death.

Keywords

Infection; Cerebral Hemorrhage; Mortality; Sub-Saharan Africa

Conflicts of Interest

The authors declare no conflicts of interest.

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