Spontaneous Regression of a Histologically Proven Cutaneous Squamous Cell Carcinoma

Sweta Sengupta, James Arocho, T. Christopher Windham

Florida Hospital Memorial Medical Center, Comprehensive Cancer Center, Memorial Hospital, Daytona Beach, USA..
Florida Hospital Memorial Medical Center, Memorial Hospital, Daytona Beach, USA.
Florida State University College of Medicine, Tallahassee, USA.

DOI: 10.4236/jct.2013.42068                

Abstract

Introduction: The rate of squamous cell carcinoma spontaneous regression (SR) remains unknown because incidences are rare and underreported. Case Report: We present a case of a 92-year-old Caucasian female who was found to have a 1 cm lesion on her nose. Pathologic evaluation supported the diagnosis of a moderately-differentiated squamous cell carcinoma. The patient refused treatment and returned with no clinical evidence of disease several months later. The lesion spontaneously regressed without excision. Discussion: Frequency of SR of malignancies has been estimated to occur 1 in 80,000 to 100,000 cases [1]. The biologic mechanisms of SR in malignancies remain unclear. Further investigations into the mechanisms of SR may identify potential treatment strategies for cancer.

Keywords

Squamous Cell Carcinoma; Spontaneous Remission

Conflicts of Interest

The authors declare no conflicts of interest.

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