A Case of Secondary Iris Cyst AfterPupilloplasty*

Abstract

Purpose: To investigate the pathogenesis of a secondary iris cyst with an immunohistochemical method. Methods: Single observational case report. A pathologic specimen was obtained from a 5-year-old girl who was found to have a secondary iris cyst. She had a history of previous penetrating ocular trauma and subsequent cataract surgery and pupilloplasty. Immunohistochemical staining with cytokeratin (CK) 19 and CK3 was used. Results: After immunohistochemical staining, the inner wall showed positive staining for CK19, which is specific for limbal, peripheral cornea and conjunctival epithelium, and negative staining for CK3, which is specific for corneal epithelium. Conclusions: With the aid of immunohistochemical analysis, a conjunctival epithelial origin was indicated, and pupilloplasty was identified as the causal event of the iris cyst while the possibility of primary iris cyst was ruled out.

Share and Cite:

Lee, J. , Kim, S. , Koh, E. and Chang, J. (2013) A Case of Secondary Iris Cyst AfterPupilloplasty*. Open Journal of Ophthalmology, 3, 13-15. doi: 10.4236/ojoph.2013.31004.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] [1] F. A. Marigo and P. T. Finger, “Anterior Segment Tumors: Current Concepts and Innovations,” Survey of Ophthalmology, Vol. 48, No. 6, 2003, pp. 569-593. doi:10.1016/j.survophthal.2003.08.001
[2] M. Küchle and W. R. Green, “Epithelial Ingrowth: A Study of 207 Histopathologically Proven Cases,” German Journal of Ophthalmology, Vol. 5, No. 4, 1996, pp. 211- 223.
[3] D. C. Cogan, “Experimental Implants of Conjunctiva into the Anterior Chamber,” American Journal of Ophthalmology, Vol. 39, No. 4, 1955, pp. 165-172.
[4] J. V. Jester, R. A. Villasenor and J. Miyashiro, “Epithelial Inclusion Cysts Following Radial Keratotomy,” Archives of Ophthalmology, Vol. 101, No. 4, 1983, pp. 611-615. doi:10.1001/archopht.1983.01040010611018
[5] T. Kivela, J. Jaaskelainen, A. Vaheri and O. Carpen, “Ezrin, a Membrane-Organizing Protein, as a Polarization Marker of the Retinal Pigment Epithelium in Vertebrates,” Cell and Tissue Research, Vol. 301, No. 2, 2000, pp. 217-223. doi:10.1007/s004410000225

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.