[1]
|
Haddad, J.J. (2008) The regulation of neuroimmune-endocrine interactions: Mechanisms, molecular pathways unraveled and the pivotal role of cytokines—A unsung putative bidirectional interdependence between the immune and neuroendocrine interfaces. Current Immunology Reviews, 4, 134-158.
doi:10.2174/157339508785160723
|
[2]
|
Welsh, C.J., Steelman, A.J., Mi, W., Young, C.R., Storts, R., Welshm Jr., T.H. and Meagher, M.W. (2009) Neuroimmune interactions in a model of multiple sclerosis. Annals of the New York Academy of Science, 1153, 209-219. doi:10.1111/j.1749-6632.2008.03984.x
|
[3]
|
Haddad, J.J., Saadé, N.E. and Safieh-Garabedian, B. (2002) Cytokines and neuro-immune-endocrine interactions: A role for the hypothalamic-pituitary-adrenal revolving axis. Journal of Neuroimmunology, 133, 1-19.
doi:10.1016/S0165-5728(02)00357-0
|
[4]
|
Bach, J., Bardenne, M., Pleau, J. and Rosa, J. (1977) Biochemical characterization of a serum thymic factor. Nature, 266, 55-57. doi:10.1038/266055a0
|
[5]
|
Millington, G. and Buckingham, J.C. (1992) Thymic peptides and neuroendocrine-immune communication. Journal of Endocrinology, 133, 163-168.
doi:10.1677/joe.0.1330163
|
[6]
|
Dardenne, M. (1999) Role of thymic peptides as transmitters between the neuroendocrine and immune systems. Annals of Medicine, 2, 34-39.
|
[7]
|
Dardenne, M., Pleau, J.M. and Bach, J.F. (1980) Evidence of the presence in normal serum of a carrier of the serum thymic factor (FTS). Journal of Immunology, 17, 83-94.
|
[8]
|
Dardenne, M., Pleau, J.M., Savino, W., Prasad, A.S. and Bach, J.F. (1993) Biochemical and biological aspects of the interaction between thymulin and zinc. Progress in Clinical and Biological Research, 380, 23-32.
|
[9]
|
Prasad, A.S. (2008) Clinical, immunological, anti-inflammatory and antioxidant roles of zinc. Experimental Gerontology, 43, 370-377.
doi:10.1016/j.exger.2007.10.013
|
[10]
|
Prasad, A.S. (2007) Zinc: Mechanisms of host defense. Journal of Nutrition, 137, 1345-1349.
|
[11]
|
Safieh-Garabedian, B., Ahmed, K., Khamashta, M.A., Taub, N.A. and Hughes, G.R. (1993) Thymulin modulates cytokine release by peripheral blood mononuclear cells: A comparison between healthy volunteers and patients with systemic lupus erythematosus. International Archives of Allergy and Immunology, 101, 126-131.
doi:10.1159/000236509
|
[12]
|
Safieh-Garabedian, B., Jalakhian, R.H., Saadé, N.E., Haddad, J.J., Jabbur, S.J. and Kanaan, S.A. (1996) Thymulin reduces hyperalgesia induced by peripheral endotoxin injection in rats and mice. Brain Research, 717, 179-183.
doi:10.1016/0006-8993(95)01532-9
|
[13]
|
Safieh-Garabedian, B., Ochoa-Chaar, C.I., Poole, S., Massaad, C.A., Atweh, S.F., Jabbur, S.J. and Saadé, N.E. (2003) Thymulin reverses inflammatory hyperalgesia and modulates the increased concentration of proinflammatory cytokines induced by i.c.v. endotoxin injection. Neuroscience, 121, 865-873.
doi:10.1016/S0306-4522(03)00500-1
|
[14]
|
Haddad, J.J., Land, S.C., Saadé, N.E. and Safieh-Garabedian, B. (2000) Immunomodulatory potential of thymulin-Zn2+ in the alveolar epithelium: Amelioration of endotoxin-induced cytokine release and partial amplification of a cytoprotective IL-10-sensitive pathway. Biochemical and Biophysical Research Communication, 274, 500-505. doi:10.1006/bbrc.2000.3155
|
[15]
|
Saadé, N.E., Atweh, S.F., Jabbur, S.J., Dardenne, M., Bach, J.F. and Safieh-Garabedian, B. (2003) A thymulin analogue peptide with powerful inhibitory effects on pain of neurogenic origin. Neuroscience, 119, 155-165.
doi:10.1016/S0306-4522(03)00072-1
|
[16]
|
Hadley, A.J., Rantle, C.M. and Buckingham, J.C. (1997) Thymulin stimulates corticotrophin release and cyclic nucleotide formation in the rat anterior pituitary gland. Neuroimmunomodulation, 4, 62-69.
|
[17]
|
Safieh-Garabedian, B., Poole, S., Haddad, J.J., Massaad, C.A., Jabbur, S.J. and Saadé, N.E. (2002) The role of the sympathetic efferents in endotoxin-induced localized inflammatory hyperalgesia and cytokine upregulation. Neuropharmacology, 42, 864-872.
doi:10.1016/S0028-3908(02)00028-X
|
[18]
|
Dardenne, M., Saadé, N. and Safieh-Garabedian, B. (2006) Role of thymulin or its analogue as a new analgesic molecule. Annals of the New York Academy of Science, 1088, 153-163. doi:10.1196/annals.1366.006
|
[19]
|
Safieh-Garabedian, B., Dardenne, M., Pléau, J.M. and Saadé, N.E. (2002) Potent analgesic and anti-inflammatory actions of a novel thymulin-related peptide in the rat. British Journal of Pharmacology, 136, 947-955.
doi:10.1038/sj.bjp.0704793
|
[20]
|
Reggiani, P.C., Morel, G.R., Cónsole, G.M., Barbeito, C.G., Rodriguez, S.S., Brown, O.A., Bellini, M.J., Pléau, J.M., Dardenne, M. and Goya, R.G. (2009) The thymus-neuroendocrine axis: Physiology, molecular biology, and therapeutic potential of the thymic peptide thymulin. Annals of the New York Academy of Science, 1153, 98-106.
doi:10.1111/j.1749-6632.2008.03964.x
|
[21]
|
Mutchnick, M.G., Good, A.E., Barlas, N. and Trainin, N. (1982) Thymic humoral factor effect on intracellular lymphocyte cAMP in patients with ankylosing spondylitis. Journal of Rheumatology, 9, 627-629.
|
[22]
|
Brown, O.A., Sosa, Y.E., Dardenne, M., Pléau, J.M. and Goya, R.G. (2000) Studies on the gonadotropin-releasing activity of thymulin: Changes with age. Journal of Gerontology, 55, B170-B176.
doi:10.1093/gerona/55.4.B170
|
[23]
|
Rinaldi-Garaci, C., Jezzi, T., Baldassarre, A.M., Dardenne, M., Bach, J.F. and Garaci, E. (1985) Effect of thymulin on intracellular cyclic nucleotides and prostaglandins E2 in peanut agglutinin-fractionated thymocytes. European Journal of Immunology, 15, 548-552.
doi:10.1002/eji.1830150604
|
[24]
|
Haddad, J.J. and Land, S.C. (2000) O2-evoked regulation of HIF-1a and NF-kB in perinatal lung epithelium requires glutathione biosynthesis. American Journal of Physiology Lung Cellular and Molecular Physiology, 278, L492-L503.
|
[25]
|
Haddad, J.J., Olver, R.E. and Land, S.C. (2000) Antioxidant/pro-oxidant equilibrium regulates HIF-1a and NF-kB redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells. Journal of Biological Chemistry, 275, 21130-21139.
doi:10.1074/jbc.M000737200
|
[26]
|
Yang, J.P., Merin, J.P., Nakano, T., Kato, T., Kitade, Y. and Okamoto, T. (1995) Inhibition of the DNA-binding activity of NF-kB by gold compounds in vitro. FEBS Letters, 361, 89-96. doi:10.1016/0014-5793(95)00157-5
|
[27]
|
Kanaan, S.A., Saadé, N.E., Haddad, J.J., Abdelnoor, A.M., Atweh, S.F., Jabbur, S.J. and Safieh-Garabedian, B. (1996) Endotoxin-induced local inflammation and hyperalgesia in rats and mice: A new model for inflammatory pain. Pain, 66, 373-379. doi:10.1016/0304-3959(96)03068-0
|
[28]
|
Senftleben, U., Li, Z.W., Baud, V. and Karin, M. (2001) IKKb is essential for protecting T cells from TNFa-induced apoptosis. Immunity, 14, 217-230.
doi:10.1016/S1074-7613(01)00104-2
|
[29]
|
Brown, O.A., Sosa, Y.E., Dardenne, M., Pléau, J. and Goya, R.G. (1999) Growth hormone-releasing activity of thymulin on pituitary somatotropes is age dependent. Neuroendocrinology, 69, 20-27. doi:10.1159/000054399
|
[30]
|
Wall, E.A., Zavzavadjian, J.R., Chang, M.S., Randhawa, B., Zhu, X., Hsueh, R.C., Liu, J., Driver, A., Bao, X.R., Sternweis, P.C., Simon, M.I. and Fraser, I.D. (2009) Suppression of LPS-induced TNF-a production in macrophages by cAMP is mediated by PKA-AKAP95-p105. Science Signaling, 2, ra28. doi:10.1126/scisignal.2000202
|
[31]
|
Qi, X.F., Kim, D.H., Yoon, Y.S., Li, J.H., Song, S.B., Jin, D., Huang, X.Z., Teng, Y.C. and Lee, K.J. (2009) The adenylyl cyclase-cAMP system suppresses TARC/CCL17 and MDC/CCL22 production through p38 MAPK and NF-kB in HaCaT keratinocytes. Molecular Immunology, 46, 1925-1934. doi:10.1016/j.molimm.2009.03.018
|
[32]
|
Henriques-Coelho, T., Oliveira, S.M., Moura, R.S., Roncon-Albuquerque Jr., R., Neves, A.L., Santos, M., Nogueira-Silva, C., La Fuente Carvalho, F., Brand?o-Nogueira, A., Correia-Pinto, J. andLeite-Moreira, A.F. (2008) Thymulin inhibits monocrotaline-induced pulmonary hypertension modulating interleukin-6 expression and suppressing p38 pathway. Endocrinology, 149, 4367-4373.
doi:10.1210/en.2008-0018
|
[33]
|
Yasuda, J., Nishioka, W., Sakudo, A., Yama, S., Setoguchi, R., Saeki, K., Matsumoto, Y., Awaya, A. and Onodera, T. (2003) Suppressor mechanism of serum thymic factor on tumor necrosis factor-a-induced apoptosis in the mouse pancreatic beta-cell line. Biochemical and Biophysical Research Communication, 311, 501-505.
doi:10.1016/j.bbrc.2003.10.025
|
[34]
|
Haddad, J.J. and Abdel-Karim, N.E. (2011) NF-kB cellular and molecular regulatory mechanisms and pathways: Therapeutic pattern or pseudoregulation? Cellular Immunology, 271, 5-14. doi:10.1016/j.cellimm.2011.06.021
|