Allergic Contact Dermatitis from Diethyl Sebacate in a Topical Antimycotic Medicament

Ayaka Hirao, Naoki Oiso, Megumi Hama, Noriko Higashimori, Yoichi Tatsumi, Akira Kawada

Departments of Dermatology, Kinki University Faculty of Medicine, Osaka, Japan.
Departments of Patient Safety and Management, Kinki University Faculty of Medicine, Osaka, Japan.

DOI: 10.4236/jcdsa.2012.23040                

Abstract

Diethyl sebacate is used in topical medicaments in United States and Japan. We described a case of allergic contact dermatitis from diethyl sebacate in a topical antimycotic medicament. Allergic reaction to diethyl sebacate is likely more common because our group has found three of eight sensitized cases. We believe that an investigation regarding the sensitized frequency to diethyl sebacate would conduct to improve the safety of products in United States and Japan.

Keywords

Allergic Contact Dermatitis; Patch Test; Allergen; Diethyl Sebacate; Safety Evaluation

Conflicts of Interest

The authors declare no conflicts of interest.

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