Ultrasonically Assisted Regioselective Nitration of Aromatic Compounds in Presence of Certain Group V and VI Metal Salts

Sariah Sana, Kamatala Chinna Rajanna, Kancharla Rajendar Reddy, Muddam Bhooshan, Marri Venkateswarlu, Mukka Satish Kumar, Kusampally Uppalaiah

Department of Chemistry, Osmania University, Hyderabad, India.

DOI: 10.4236/gsc.2012.23015                

Abstract

Ultrasonically assisted nitration reactions (USANR) with anilides, moderately activated and non-activated aromatic compounds underwent smoothly and afforded good yields of products with high regio selectivity. Observed longer reaction times (6 - 8 hrs.) in metal catalyzed reactions reduced to (1 - 2 hrs.) under sonication. When ortho position is blocked para derivatives are obtained, and ortho nitro products are obtained when para position is blocked. In case of USANR of aromatic carbonyl and related compounds the effect of sonication is much more effective. The reactions could be completed only in few minutes.

Keywords

Ultrasonically Assisted; Regioselective Nitration; Group V and VI Metal Salts; Reduction in Reaction Times

Conflicts of Interest

The authors declare no conflicts of interest.

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