A Novel Antibacterial Dental Resin Composite

Yiming Weng, Voon J. Chong, Leah Howard, Ruijie Huang, Richard L. Gregory, Dong Xie

Department of Biomedical Engineering, Purdue School of Engineering and Technology Indiana University-Purdue University at Indianapolis, Indianapolis, USA.
Department of Oral Biology, School of Dentistry, Indiana University Indianapolis, USA.

DOI: 10.4236/jbnb.2012.32018                

Abstract

This study reports the synthesis and evaluation of a novel furanone-containing antibacterial resin composite. Compres-sive strength (CS) and S. mutans viability were used to evaluate the mechanical strength and antibacterial activity of the composites. With 5% to 30% addition of the furanone derivative, the composite showed no change in CS but a significant antibacterial activity with a 16% - 68% reduction in the S. mutans viability. Further, the antibacterial activity of the modified composite was not affected by human saliva. The aging study implies that the modified composite may have a long-lasting antibacterial function. Within the limitations of this study, it appears that this experimental resin composite may potentially be developed into a clinically attractive dental restorative due to its high mechanical strength and antibacterial function.

Keywords

Furanone Derivative; Antibacterial; Resin Composite; CS; S. mutans Viability

Conflicts of Interest

The authors declare no conflicts of interest.

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