Gallic Acid-loaded Cellulose Acetate Electrospun Nanofibers: Thermal Properties, Mechanical Properties, and Drug Release Behavior

Manisara Phiriyawirut, Thawatchai Phaechamud

Department of Pharmaceutical Technology, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand.
Department of Tool and Materials Engineering, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand.

DOI: 10.4236/ojpchem.2012.21004                

Abstract

The gallic acid-loaded electrospun cellulose acetate fibers were successfully prepared. The fiber containing 2.5% gallic acid was smooth surface but observed drug flake on the surface of the fiber when increasing drug content. The thermal properties, mechanical properties and drug release behavior of the fibers were investigated comparing to the corres-ponding films.

Keywords

Electrospinning; Gallic Acid; Cellulose Acetate; Melting; Drug Release

Conflicts of Interest

The authors declare no conflicts of interest.

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