Appendical Perforation by Infection with Extended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli: Case Report

Hisayuki Miyagi, Tadao Okada, Shohei Honda, Masashi Minato, Akinobu Taketomi

Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Department of Pediatric Surgery, Hokkaido University Hospital, Sapporo, Japan.

DOI: 10.4236/ss.2012.31009                

Abstract

We report the very rare case of a huge appendical abscess with extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (E. coli) as the pathogen. There have been several reports of appendical infections such as appendicitis and appendical abscess caused by ESBL-producing bacteria in adults. The treatment of ESBL-producing E. coli infection is specific, and ESBL-producing bacteria have recently been reported as pathogens associated appendicitis in children. To the best of our knowledge, this is the second report of perforated appendicitis with abscess due to ESBL-producing E. coli. We discuss the diagnostic modalities and treatments for appendical abscess with ESBL-producing E. coli. and propose that the patients with perforated appendicitis and abscess formation due to ESBL-producing E. coli should be administered the antibiotic MEPM within 2 weeks to treat the abscess more effec-tively without producing other multidrug-resistant bacteria.

Keywords

Appendicitis; ESBL (Extended-Spectrum Beta-Lactamase)-Producing E. coli; Abscess; Meropenem

Conflicts of Interest

The authors declare no conflicts of interest.

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