ABSTRACT
Background and Aims: The treatment of patients with advanced cancer pain is mainly
concentrated in the outpatient department, and most of the time in their
family, these patients are easy to be ignored, To study the quality of life and its influencing
factors of cancer pain patients at home is of great significance to improve the
quality of life of patients. Meanwhile, it provides theoretical and practical basis for medical personnel to develop
and implement individualized comprehensive intervention programs. Patients
and Methods: According to the inclusion and exclusion criteria, 200
patients with cancer pain at home are selected to treat, and their quality of
life conditions are observed before treatment, 1 week after treatment and 1
month after treatment, and their influencing factors are analyzed. Results: The
patients’ scores of body function, emotional function, cognitive function and social function exist
significant difference before and after treatment (p < 0.01), the scores of role function and the
overall evaluation scores before and after treatment, two stages after treatment exist significant difference (p <
0.01), the symptoms scores of fatigue, pain, diarrhea, nausea and vomiting are
significant differences before and after treatment (p < 0.01); appetite loss score before a month and a week after
treatment and treatment exists significant difference (p < 0.01), the scores of constipation
symptom before treatment and a
month after treatment exist significant difference (p < 0.01), only gender
on cognitive function before treatment has significant difference (p < 0.05). One week after treatment,
tumor staging and metastasis have impact on overall health evaluation, role
function, cognitive function and emotional function (p < 0.05). The location of metastasis
and the type of pain affect the role function and emotional function
respectively (p < 0.05). One month after treatment, age, metastasis, metastasis site and pain type have influence on cognitive function, emotional function, overall health
evaluation and role function respectively (p < 0.05). The overall health status,
body function, role function, emotional function, cognitive function and social
function of the patients are lower than those of the Norwegian norm (p <
0.001). The symptoms of pain, appetite, constipation, nausea and vomiting are higher than those of the
Norwegian norm before and after treatment (p < 0.001). There was a significant
positive correlation between quality of life and total score of social support (p < 0.01). Objective support and subjective
support were positively correlated with quality of life (p < 0.01). Conclusion: Cognitive interventions should be individualized. The effectiveness of cancer
treatment and the control of cancer recurrence and metastasis have influence on the quality of life of patients
with cancer pain at home. Although
the patients’ function indexes have been improved after treatment, there exist differences
in the improvement after treatment. The symptoms of nausea, vomiting, pain and appetite should be intervened promptly. The
management of symptoms such as dyspnea, fatigue, constipation should be focused
persistently. Objective support and subjective support were the influencing
factors of patients’ quality of life, the construction of social support system should be strengthened, we should help them to
overcome negative emotions, return to normal family and social roles, seek help
in a positive manner and use support to improve the quality of life.