Author(s)

Liumei Luo¹, Juncheng Guo^2*, Xiang Li³, Min Guo¹, Ping Huang⁴

¹Hainan General Hospital, Sanya, China.
²Haikou Hospital Affiliated to Xiangya School of Medicine, Central South University, Haikou, China.
³The Third People’s Hospital of Hubei Province, Wuhan, China.
⁴University of South China, Hengyang, China.

In the regulation of human nervous system, cognitive function and other genes, epigenetics changes the expression of genes after being influenced by the external environment. DNA methylation levels are also different in different ethnic groups, and a large number of studies have shown that post-traumatic stress disorder (PTSD) has a certain genetic predisposition. Through the national differences of PTSD brain-derived neurotrophic factor genes, it not only provides new research directions for the pathogenesis and treatment of 5-HT-related mental diseases, but also provides information and new genetic indicators for forensic personal identification, paternity testing and assessment of mental status. A review studies on the national differences of brain-derived neurotrophic factor genes in patients with post-traumatic stress disorder.

Ethnicity, Post-Traumatic Stress Disorder, Brain-Derived Neurotrophic Factor, Gene Methylation

Luo, L. , Guo, J. , Li, X. , Guo, M. and Huang, P. (2019) A Review of Studies on Ethnic Differences of Brain-Derived Neurotrophic Factor Genes in Patients with Post-Traumatic Stress Disorder. World Journal of Neuroscience, 9, 229-242. doi: 10.4236/wjns.2019.94017.