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Efficient Cross-Coupling Reaction of Aryltrifluoroborates and Aroyl Chlorides for the Synthesis of Fluorine Substituted Aromatic Ketones

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DOI: 10.4236/ijoc.2019.91006    260 Downloads   548 Views

ABSTRACT

The direct aroylation of ArCOPdCl with potassium aryltrifluoroborates establishes a new cross-coupling synthetic tool for the synthesis of various fluorine substituted benzophenones. The new microwave irradiated process is very efficient and produce high yield benzophenone products within minutes.

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Al-Masum, M. , Islam, T. and Clopton, G. (2019) Efficient Cross-Coupling Reaction of Aryltrifluoroborates and Aroyl Chlorides for the Synthesis of Fluorine Substituted Aromatic Ketones. International Journal of Organic Chemistry, 9, 67-72. doi: 10.4236/ijoc.2019.91006.

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