Share This Article:

Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-b]Indole Moiety as Antifungal Agents

Full-Text HTML XML Download Download as PDF (Size:1018KB) PP. 37-46
DOI: 10.4236/ijoc.2019.91004    211 Downloads   446 Views

ABSTRACT

Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thiophenol and/or cycloaddition with thiolactic acids in nonpolar solvents. Structures of the products confirmed by elemental analysis and spectral measurements. The new systems obtained were evaluated as antifungal agents.

Cite this paper

Bawazir, W. (2019) Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-b]Indole Moiety as Antifungal Agents. International Journal of Organic Chemistry, 9, 37-46. doi: 10.4236/ijoc.2019.91004.

Copyright © 2018 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.